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MathBio Seminar

Monday, March 14, 2016 - 4:00pm

David Holcman

École Normale Supérieure

Location

University of Pennsylvania

318 Carolyn Lynch Lab

The organization and the dynamics of chromatin in the cell nucleus are still not resolved. Experimental and theoretical approaches are now converging and I propose to summarize recent progress using polymer models, mathematical analysis for studying stochatic single particle trajectories. Finally, we will discuss asymptotic methods for estimating the mean time for a polymer to loop, interpreting large data sets and reconstructing chromatin organization.