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MathBio Seminar

Monday, April 10, 2017 - 4:00pm

Jeff Wall



University of Pennsylvania

318 Carolyn Lynch Lab

The GenomeAsia 100K consortium plans to generate high-coverage whole-genome sequence data from 100,000 Asian individuals over the next ~3 years, as a way of facilitating future sequence-based biomedical studies in Asian populations. I will discuss some initial analyses of the pilot phase of the project, consisting of 1,739 genomes from ~200 different populations. These will include analyses of the historical branching order of populations, contributions of Neanderthal, Denisovan and other archaic human groups to modern human genomes, estimates of the 1000 Genomes Project genotype call error rate, and estimates of the somatic mutation rate in cell lines.