Rapid evolution in response to environmental change is common in microbes and other species with short generation times, but can it also rescue long-lived organisms like mammals and fishes? This talk will present evidence from temporal genomic approaches to reveal where and how species are evolving to cope with a quickly changing environment. Examples include bats infected with a novel disease and intensely fished populations of Atlantic cod. New genomic tools and approaches are providing unprecedented insight into the largely invisible evolution happening all around us.